Bristol Myers ends Cellares deal over Breyanzi scale-up

Reuters · 3 days ago
  • Bristol Myers Squibb ended its partnership with Cellares to expand manufacturing of its personalized blood cancer therapy Breyanzi.
  • Bristol Myers said Cellares' Cell Shuttle platform could not meet the requirements to manufacture Breyanzi at commercial scale, while Cellares disputed that assessment.
  • Cellares will lay off about 100 employees at its South San Francisco facility on October 20 after losing the large pharmaceutical customer.
  • Breyanzi generated $1.36 billion in sales in 2025, and the 2024 partnership was valued at up to $380 million.

Quotes

could not meet the requirements to make its CAR-T therapy, Breyanzi, at commercial scaleBristol Myers Squibb spokesperson
Cellares strongly disagrees with this characterizationCellares
large pharmaceutical customerFabian Gerlinghaus

Sources